In 2022, NACo convened an advisory board of national experts and leading researchers to analyze Exhibit E of the national opioid settlement agreements. Exhibit E outlines a non-exhaustive list of over 130 approved uses of opioid settlement funds that qualify as “opioid remediation.” NACo’s Opioid Solutions Strategy Briefs document 15 high-impact opioid abatement strategies from this list that are under county authority. Each brief summarizes the available evidence, best practices for implementation, county examples and links to additional resources, including opportunities for specialized technical assistance.

In 2022, NACo convened an advisory board of national experts and leading researchers to analyze Exhibit E of the national opioid settlement agreements. Exhibit E outlines a non-exhaustive list of over 130 approved uses of opioid settlement funds that qualify as “opioid remediation.” NACo’s Opioid Solutions Strategy Briefs document 15 high-impact opioid abatement strategies from this list that are under county authority. Each brief summarizes the available evidence, best practices for implementation, county examples and links to additional resources, including opportunities for specialized technical assistance.

Key Strategies

Several strategies are commonly regarded as pillars of response to opioid use disorder. These strategies span the substance use continuum of care – from prevention, to harm reduction, treatment and recovery. 

County leaders who are new to the field of substance use or interested in investing in time-tested strategies may find the strategy briefs to the right helpful.

Casual conversation between adult and students

Youth-Focused Prevention: A NACo Opioid Solutions Strategy Brief

Youth-focused programs, including school-based programs, may help support young people and their families, strengthen community connections and mitigate the long-term negative impacts of adverse childhood experiences. 

Image of Naloxone_cover.jpg

Naloxone to Reverse Opioid Overdose

Naloxone is a “rescue” drug that quickly and safely reverses opioid overdose. It is available as an injectable solution and as a nasal spray. Naloxone works by blocking the effects of opioids in the body. Virtually all opioid overdose deaths are preventable if naloxone is administered in time. 

Image of Thumbnail_Tile 2.png

Syringe Services Programs: A NACo Opioid Solutions Strategy Brief

Syringe services programs (SSPs) provide low-barrier access to sterile supplies for safer substance use, naloxone and overdose prevention tools like fentanyl test strips and drug checking services. SSPs also provide a range of other services, such as options for safe syringe disposal, overdose recognition and response training and help accessing services for HIV, substance use disorders and more. 

Image of OSC_Strategy_MOUD_Cover.jpg

Medication-Assisted Treatment (“MAT”) for Opioid Use Disorder: A NACo Opioid Solutions Strategy Brief

The Food and Drug Administration (FDA) has approved three medications that safely and effectively treat opioid use disorder (OUD) to improve the health and wellbeing of people living with OUD. MAT is defined by on-going, long-term treatment with one of these three medications. 

Improving Access Across Systems

Counties oversee a myriad of service systems – from public health to law enforcement, human services and emergency response – that serve communities affected by substance use disorder. From this unique position, county leaders play a pivotal role in fostering collaboration across systems and ensuring that individuals who are engaged in other systems will be aware of and connected with MOUD.

The strategies to the right outline ways by which county leaders can promote a more integrated service system for individuals affected by SUD and make systems change that increases access to care.

Physician at desk looking at computer talking on phone

Linkage to Care Across County Systems: A NACo Opioid Solutions Strategy Brief

As the owners and operators of systems of service that regularly interface with people affected by substance use such as hospitals, jails, courts and community colleges, counties are well positioned to link community members with evidence-based options for care, especially medications for opioid use disorder (MOUD). 

adult in therapy session

Comprehensive Services for People With Co-Occurring Disorders: A NACo Opioid Solutions Strategy Brief

Comprehensive services integrate multiple forms of substance use, mental health and case management services and may include: evidence-based treatments for SUD, integrated mental health treatment services, housing support, transportation support, employment and educational services, income support, social support, legal services and child care. 

Image of AccesstoTxCover.jpg

Increasing Access to Evidence-Based Treatment: A NACo Opioid Solutions Strategy Brief

Our health care system’s capacity to provide medications for opioid use disorder (MOUD) falls far below the current demand for care. Only 1 in 4 people who need MOUD are able to access them. A multi-pronged approach is needed to build up the treatment workforce, create effective pathways to care and save lives. 

Doctor in plain clothes discussing document with patient

Warm Hand-Offs: A NACo Opioid Solutions Strategy Brief

A warm hand-off is a form of referral to treatment or other services. A typical referral gives someone information about how to reach the services they need but may leave them to contact those services on their own. In contrast, a warm hand-off is a transfer of care between service providers through face-to-face, phone or video interaction in the presence of the person being helped.

Image of PORT Cover.jpg

Post-Overdose Response Teams

Post-overdose response teams (also called quick response teams or post-overdose outreach programs) conduct outreach and offer services to people who have experienced an overdose within about 72 hours of the overdose event.

Improving Access for Specific Communities

Counties often have a strong role in human services and corrections. As a result, county leaders can have a considerable impact on the communities served by these systems – families and people with criminal legal system involvement – by dismantling the specific barriers and meeting their unique needs. 

Families

Pregnant and parenting people affected by substance use disorder and infants affected by neonatal abstinence syndrome are at a crucial juncture for treatment. Increasing access to and removing the stigma around medications for opioid use disorder (MOUD) strengthens families and supports recovery. 

The strategy briefs to the right address these best practices.

Image of Thumbnail_Tile 4.png

Treatment and Recovery for Pregnant and Parenting People: A NACo Opioid Solutions Strategy Brief

Effective treatment for pregnant and parenting people means expanding access to MOUD and adopting a family-centered approach that prioritizes keeping families together.

Image of NAS Cover_v2.jpg

Treatment for Neonatal Abstinence Syndrome: A NACo Opioid Solutions Strategy Brief

Neonatal Abstinence Syndrome or NAS (also called Neonatal Opioid Withdrawal Syndrome or NOWS) is a condition that sometimes affects newborns of parents who have taken opioids during pregnancy. Because NAS does not cause long-term health consequences, treatment with MOUD – as opposed to withdrawal and abstinence – is safer for both parents and their infants.

People Impacted by the Criminal Legal System

Incarceration is a primary risk factor for overdose. Within the first two weeks of release, formerly incarcerated individuals are 40 times more likely to experience an overdose than the general population. Increasing access to MOUD in the criminal legal system can save lives, reduce recidivism and promote recovery. 

The strategy briefs to the right address these targeted interventions across the criminal legal system – from pre-arrest to release from incarceration. 

A counselor reassures a client

Pre-Arrest Diversion: A NACo Opioid Solutions Strategy Brief

Pre-arrest diversion strategies enable law enforcement officers to refer community members with unmet needs to trauma-informed case management and support services in lieu of arrest, prosecution and incarceration.

PretrialServices_thumbnail

Pretrial Services for People with Opioid Use Disorder

Pretrial services typically consist of assessments and decisions concerning bail, release and community supervision in anticipation of future court appearances. These processes provide important opportunities to engage local health care and social services providers and link defendants and their families to the care that they need.

Image of Thumbnail_Tile 3.png

Effective Treatment for Opioid Use Disorder for Incarcerated Populations: A NACo Opioid Solutions Strategy Brief

Medication-assisted treatment (MAT) is considered the “gold standard” of care for opioid use disorder (OUD). Because incarceration is a known driver of opioid overdose, failure to provide this gold standard of care to incarcerated individuals may exacerbate health risks in your community.

Man and woman embracing in doorway

Coordination of Care Upon Release From Incarceration: A NACo Opioid Solutions Strategy Brief

Coordination of care upon release is the deliberate organization and sharing of information between correctional and community-based service providers to ensure the most effective care for each person returning to the community. 

Related News

Oakland County, Mich. Commissioner Yolanda Smith Charles discusses housing needs at a press conference. Photo courtesy of Yolanda Smith Charles
County News

Commissioner fights for ‘forgotten’ township

Yolanda Smith Charles has championed a small municipality in her Oakland County, Mich. district that has been dismantled as others grow.

EPA staff meet with county officials at the 2025 NACo Legislative Conference. Photo by Denny Henry
County News

NACo to kick off 2026 Legislative Conference, unveil ‘We Are Counties’ message

More than 2,000 county officials from across the nation are visiting Washington, D.C., for NACo 2026 Legislative Conference, at the Washington Hilton Feb. 21-24.

bike
Advocacy

Local government organizations send letter in support of the BASICS Act to congressional leaders

On February 16, nearly 80 state associations of counties and municipal leagues representing local governments in all 50 states sent a letter to the leaders of the U.S. House Committee on Transportation and Infrastructure and the U.S. Senate Committee on Environment and Public Works expressing their support for the Bridges And Safety Infrastructure for Community Success (BASICS) Act (H.R. 7437) and urging its inclusion in the next surface transportation reauthorization bill. 

Crews collect debris. As of Feb. 10, Lafayette County, Miss. collected 90,000 cubic yards of debris. Photo courtesy of Beau Moore
County News

After historic winter storms, counties assess response

Counties in states that rarely receive much winter weather are assessing their responses to the January storm that left many covered in snow and ice.

A stolen backhoe being unloaded in March 2024 from a semitruck, recovered by law enforcement in Tulare County, Calif. Photo courtesy of the Tulare County Sheriff’s Office
County News

California counties fight agricultural crime

Sheriffs' offices and prosecutors in California's central valley make specific efforts to prevent and prosecute crimes against the agricultural community.

Related Events

1130838116_cmyk
Conference

2026 NACo Legislative Conference

Washington, D.C.

The NACo Legislative Conference brings together nearly 2,000 elected and appointed county officials to focus on federal policy issues that impact counties and our residents.

Finance chart
Webinar

Cyber Resilience in County Finance: Protecting What Matters Most

Friday, March 6, 2026 | 2:00 p.m. - 3:00 p.m. ET

Cyber threats are increasingly targeting public sector finance teams and resilience starts with understanding the risks. In this webinar, Peter Forsgren of three+one shares real stories from ethical hackers to explore social engineering, emerging cybersecurity threats and practical steps counties can take to protect their people, data and financial systems. 

This webinar is brought to you by NACo EDGE, establishing people, purchasing, and performance cost-saving solutions that can be applied to counties nationwide. EDGE is owned by NACo, advised by county leaders and 100% focused on solutions for U.S. Counties. Learn more about NACo EDGE here.

For more information, visit the event page!

Image of GettyImages-894378544.jpg
Webinar

NACo Policy Insider Webinar Series: Understanding the Federal Landscape for Counties, March 12

Join NACo for a bi-weekly webinar offering an overview of the full federal policy landscape impacting counties.

Image of GettyImages-894378544.jpg
Webinar

NACo Policy Insider Webinar Series: Understanding the Federal Landscape for Counties, March 26

Join NACo for a bi-weekly webinar offering an overview of the full federal policy landscape impacting counties.

Image of GettyImages-894378544.jpg
Webinar

NACo Policy Insider Webinar Series: Understanding the Federal Landscape for Counties, April 9

Join NACo for a bi-weekly webinar offering an overview of the full federal policy landscape impacting counties.

Image of GettyImages-894378544.jpg
Webinar

NACo Policy Insider Webinar Series: Understanding the Federal Landscape for Counties, April 23

Join NACo for a bi-weekly webinar offering an overview of the full federal policy landscape impacting counties.