“We all have the power to make a difference when it comes to substance misuse prevention.”  

— Dr. Miriam Delphin-Rittmon, Assistant Secretary for Mental Health and Substance Use, U.S. Department of Health and Human Services1

What does effective youth-focused prevention look like?

Adverse childhood experiences (ACEs), such as poverty, childhood abuse or neglect, and family separation, are associated with increased risk of mental health concerns and substance use in adulthood.2-5 Youth-focused programs, including school-based programs, may help support young people and their families, strengthen community connections and mitigate the long-term negative impacts of ACEs.

Youth-focused programs may involve a variety of components,6-8 including, but not limited to:

  • Health education (e.g., on the impacts of substance use)
  • Skills training for youth (e.g., life skills or socio-emotional learning)
  • Skills training for parents and caregivers (e.g., behavioral management and socio-emotional development)
  • Peer education (e.g., teaching social norms)
  • Mentoring strategies (e.g., qualified counselors in school settings)
  • Classroom-based programming (e.g., structured behavioral management strategies)
  • Afterschool programming (e.g., whole-family events)

Youth-focused programs can help counties achieve a variety of goals, including reducing the number of youth who begin using substances, reducing the risk of developing a substance use disorder and reducing the risk of overdose among young people who use drugs. Youth-focused prevention can also help counties reduce stigma, promote help-seeking among young people who may be struggling, strengthen families and community connections and improve young people’s overall social and emotional wellbeing.  

What does the evidence say about youth-focused prevention?

Though many youth-focused prevention programs have been developed and evaluated, few have proved effective. Of the youth-focused prevention programs that have been evaluated, most take place in school settings. Some have no impact on any type of substance use, while others may only reduce certain types of substance use among some youth.9 Programs that do impact substance use generally produce modest protective effects (e.g., reducing youth cannabis and other substance use by 15-20 percent) that subsequently fade over time.8,10 Collectively, the evidence shows that young people may use drugs even after receiving the very best prevention programing.

Certain program characteristics are associated with better outcomes. Programs that are delivered through 15 or more sessions, interactive, led by a trained adult other than the participants’ school teacher and target high school (as opposed to middle or elementary school) students are moderately effective.11,12 Limited evidence also supports combining social competence and social influence approaches and adopting a skills-based approach.8

The most effective programs are those that adopt social competency and social influence approaches. This includes approaches such as teaching social skills, supporting emotional and behavioral regulation and normalizing delaying or never initiating substance use.8 Further, different programs are more effective for different age groups. For example, programs focused on emotional and behavioral regulation are most effective among young children. Interventions focused on social norms, such as correcting misperceptions about substance use among peers, are most effective among early adolescents.6

Are there risks to my community or institution if we don’t support youth-focused prevention?

Yes and no.

Childhood and adolescence are ideal periods to invest in the health and wellness of the entire community by responding to ACEs and reducing their impact on young people’s lives.2–5 When implemented appropriately, interventions that promote safe and stable school environments and stronger family connections can positively impact youth health and wellbeing far beyond matters of substance use.13

At the same time, prevention efforts that are poorly delivered (e.g., deviating from the standardized intervention or delivered by unqualified adults) or are inappropriate for a particular population or age group can worsen substance use-related outcomes. In particular, programs that target or cluster high-risk students together may succeed in normalizing, rather than preventing, risky behaviors, resulting in higher rates of substance use.6,14,15 Programs that rely on scare tactics or strict behavioral edicts (i.e., “just say no”) have repeatedly been shown to have no impact,16 or, in some instances, to increase substance use among young people.17 

What are best practices for school-based and youth-focused prevention?

  • Support age-appropriate school-based strategies that provide different material and activities to address the unique learning needs of students in different grades.6
  • Support universal school-based programs that involve the whole student population.10
  • Support programs that integrate multiple components (e.g., strategies to support decision-making skills and health education beyond the classroom).18
  • Support strategies delivered over 15 or more sessions for adolescents.12
  • Support the inclusion of families in prevention programs through parenting or family skills training, home visits, brief family therapy, or family education.19,20
  • Support programs delivered by persons other than teachers, such as qualified health educators or counselors.11  
  • Implement these prevention programs as one part of a more comprehensive plan to address ACEs, strengthen families, teach life skills and support healthy socio-emotional development in youth.8

What are examples of successful school-based and youth-focused prevention programs?

The Good Behavior Game is a collaborative classroom activity designed to teach students in the 1st and 2nd grades to regulate their emotions and behaviors.21 Though it is designed as a classroom management strategy, program evaluations have found the Good Behavior Game to be associated with lower rates of substance use and substance use disorder in early adulthood among male students who participated in the program as children.22,23

Fast Track is an intervention designed for students in 1st to 10th grades who displayed disruptive behaviors in kindergarten.24 Fast Track includes home visits, parent mentoring, student tutoring, social skills training and classroom-based socio-emotional learning. The intervention evolves as children grow, supplementing social and emotional learning with group meetings, tutoring sessions, home visits and other developmentally-appropriate interventions across age groups. Evaluations have shown that Fast Track participants were less likely to report substance use in early adulthood.7,25

Safety First: Real Drug Education for Teens is a secondary prevention program for students in 9th and 10th grades that teaches substance awareness and overdose recognition and response.26 Safety First consists of fifteen 45-minute lessons designed to align with National Health Education Standards and Core Curriculum Standards. Evaluations have shown that Safety First participants can more accurately identify the risks of substance use and are better prepared to effectively respond to overdose and other substance-related emergencies.27

These and many other model programs are described online at the Brandeis Opioid Resource Connector.

Visit the Brandeis Opioid Resource Connector

Author

Jennifer J. Carroll, PhD, MPH

Dr. Carroll is a medical anthropologist, research scientist and subject matter expert on substance use and public health. She is currently an Assistant Professor of Anthropology at North Carolina State University.

Additional Resources

National Center of Safe Supportive Learning Environments
The National Center on Safe Supportive Learning Environments (NCSSLE) offers technical assistance and training on subjects related to student resilience and school-based mental health services for teachers, administrators, families, and students. They also offer a variety of webinars and online tools. NCSSLE accepts direct requests for technical assistance through their website.

The Center on Positive Behavioral Interventions and Supports
The Center on Positive Behavioral Interventions and Supports (PBIS) offers online tools and resources as well as technical assistance to schools and school districts implementing tiered socio-emotional and behavioral supports, including offering substance use prevention within a tiered intervention framework. Most U.S. states and territories are served by a designated PBIS state coordinator.

The Partnership to End Addiction
The Partnership to End Addiction is a national organization working to transform the United States’ approach to addiction by empowering families, advancing effective care, shaping public policy and changing culture. It offers tailored resources for families, health care providers, policymakers and advocates to learn more about prevention and early intervention, as well as a virtual learning series for county leaders.

  1. Delphin-Rittmon ME. Twitter. Published October 19, 2023. Accessed November 21, 2023. https://twitter.com/SAMHSA_Leader/status/1715095549991424279

  2. Felitti VJ, Anda RF, Nordenberg D, et al. Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults: The Adverse Childhood Experiences (ACE) Study. American Journal of Preventive Medicine. 1998;14(4):245-258. doi:10.1016/S0749-3797(98)00017-8

  3. U.S. Centers for Disease Control and Prevention. Fast Facts: Preventing Adverse Childhood Experiences. Violence PRevention. Published April 14, 2022. Accessed October 3, 2022. https://www.cdc.gov/violenceprevention/aces/fastfact.html

  4. Forster M, Rogers CJ, Benjamin SM, Grigsby T, Lust K, Eisenberg ME. Adverse Childhood Experiences, Ethnicity, and Substance Use among College Students: Findings from a Two-State Sample. Substance Use & Misuse. 2019;54(14):2368-2379. doi:10.1080/10826084.2019.1650772

  5. Merrick MT, Ford DC, Haegerich TM, Simon T. Adverse Childhood Experiences Increase Risk for Prescription Opioid Misuse. Journal of Primary Prevention. 2020;41(2):139-152.

  6. Onrust SA, Otten R, Lammers J, Smit F. School-based programmes to reduce and prevent substance use in different age groups: What works for whom? Systematic review and meta-regression analysis. Clin Psychol Rev. 2016;44:45-59. doi:10.1016/j.cpr.2015.11.002

  7. Oyserman D, Brickman D, Rhodes M. School Success, Possible Selves, and Parent School Involvement*. Family Relations. 2007;56(5):479-489. doi:10.1111/j.1741-3729.2007.00475.x

  8. Faggiano F, Minozzi S, Versino E, Buschemi D. School-based prevention for illicit drug use. Cochrane Database of Systematic Reviews. 2014;2014(12):Art. No: CD003020.

  9. Flynn AB, Falco M, Hocini S. Independent Evaluation of Middle School-Based Drug Prevention Curricula: A Systematic Review. JAMA Pediatr. 2015;169(11):1046-1052. doi:10.1001/jamapediatrics.2015.1736

  10. MacArthur G, Caldwell DM, Redmore J, et al. Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people. Cochrane Database of Systematic Reviews. 2018;(10). doi:10.1002/14651858.CD009927.pub2

  11. Das JK, Salam RA, Arshad A, Finkelstein Y, Bhutta ZA. Interventions for Adolescent Substance Abuse: An Overview of Systematic Reviews. J Adolesc Health. 2016;59(4 Suppl):S61-S75. doi:10.1016/j.jadohealth.2016.06.021

  12. Porath-Waller AJ, Beasley E, Beirness DJ. A meta-analytic review of school-based prevention for cannabis use. Health Educ Behav. 2010;37(5):709-723. doi:10.1177/1090198110361315

  13. U.S. Centers for Disease Control and Prevention. Essentials for Childhood: Creating Safe, Stable, Nurturing Relationships and Environments for All Children. Published online 2019. Accessed October 26, 2022. https://www.cdc.gov/violenceprevention/pdf/essentials-for-childhood-framework508.pdf

  14. Valente TW, Ritt-Olson A, Stacy A, Unger JB, Okamoto J, Sussman S. Peer acceleration: effects of a social network tailored substance abuse prevention program among high-risk adolescents. Addiction. 2007;102(11):1804-1815. doi:10.1111/j.1360-0443.2007.01992.x

  15. Dishion TJ, McCord J, Poulin F. When interventions harm. Peer groups and problem behavior. Am Psychol. 1999;54(9):755-764. doi:10.1037//0003-066x.54.9.755

  16. West SL, O’Neal KK. Project D.A.R.E. Outcome Effectiveness Revisited. Am J Public Health. 2004;94(6):1027-1029. doi:10.2105/AJPH.94.6.1027

  17. Rosenbaum DP, Hanson GS. Assessing the Effects of School-Based Drug Education: A Six-Year Multilevel Analysis of Project D.A.R.E. Journal of Research in Crime and Delinquency. 1998;35(4):381-412. doi:10.1177/0022427898035004002

  18. Cuijpers P. Effective ingredients of school-based drug prevention programs. A systematic review. Addict Behav. 2002;27(6):1009-1023. doi:10.1016/s0306-4603(02)00295-2

  19. Ladis BA, Macgowan M, Thomlison B, et al. Parent-Focused Preventive Interventions for Youth Substance Use and Problem Behaviors: A Systematic Review. Research on Social Work Practice. 2019;29(4):420-442. doi:10.1177/1049731517753686

  20. Kuntsche S, Kuntsche E. Parent-based interventions for preventing or reducing adolescent substance use - A systematic literature review. Clin Psychol Rev. 2016;45:89-101. doi:10.1016/j.cpr.2016.02.004

  21. Paxis Institute. School-based Programming. Paxis Institute. Published 2021. Accessed October 26, 2022. https://www.paxis.org/school-based-programming/

  22. Poduska JM, Kellam SG, Wang W, Brown CH, Ialongo NS, Toyinbo P. Impact of the Good Behavior Game, a universal classroom-based behavior intervention, on young adult service use for problems with emotions, behavior, or drugs or alcohol. Drug and Alcohol Dependence. 2008;95:S29-S44. doi:10.1016/j.drugalcdep.2007.10.009

  23. Kellam SG, Brown CH, Poduska JM, et al. Effects of a universal classroom behavior management program in first and second grades on young adult behavioral, psychiatric, and social outcomes. Drug and Alcohol Dependence. 2008;95:S5-S28. doi:10.1016/j.drugalcdep.2008.01.004

  24. Duke University Center for Child & Family Policy. Fast Track Project. Fast Track Project. Published 2022. Accessed October 26, 2022. https://fasttrackproject.org/

  25. Dodge KA, Bierman KL, Coie JD, et al. Impact of early intervention on psychopathology, crime, and well-being at age 25. Am J Psychiatry. 2015;172(1):59-70. doi:10.1176/appi.ajp.2014.13060786

  26. Halpern-Felsher REACH Lab at Stanford Medicine. Safety First. Halpern-Felsher REACH Lab. Published 2024. Accessed March 3, 2024. https://med.stanford.edu/halpern-felsher-reach-lab/preventions-interventions/Safety-First.html#resources_infographics

  27. Drug Policy Alliance. Safety First: Real Drug Education for Teens. Published online 2021. Accessed October 26, 2022. https://drugpolicy.org/sites/default/files/safety-first-fact-sheet-2021.pdf